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A pre-tour day or two is highly recommended to fully explore this magnificent city. Please contact me for booking accommodations in Rome prior to Day 1 of the Ultimate Italy itinerary.
Please note that if Vatican City is on your must-see list, I highly recommend purchasing tickets several weeks prior to your trip. Advance tickets can be reserved online at https://tickets.museivaticani.va/home. Same-day entrance to St. Peter's Basilica and the Vatican Museums (including the Sistine Chapel) cannot be guaranteed without advance tickets. I am also happy to help arrange.
I also recommend pre-booking your tickets to the Colosseum to guarantee entrance and to avoid long lines: https://ticketing.colosseo.it/en